Velpanat (Epclusa Generic) price in India

The drug Velpanat from the Indian manufacturer Natco is used to treat viral hepatitis C of all genotypes (1 to 6), regardless of the presence or absence of complications and associated infections. Velpanat is one of the most effective drugs. It is recommended for patients who are undergoing treatment for the first time and for re-treatment.

Full instructions for use in Russian are not included in the package, since Velpanat is not registered in the Russian Federation. But they are translated and available for free on the Internet. But the final treatment regimen should be acc upon by a doctor.

Dosage

Velpanat is available in the form of tablets containing the exact dose of the active ingredients.

Description and composition

Velpanat contains two substances with antiviral activity: sofosbuvir in an amount of 400 mg and velpatasvir in a dose of 100 mg (Epclusa Generic). The manufacturer does not list auxiliary components, but, according to experts, the pharmacological properties of the drug are fully consistent with the properties of the original Epclusa drug.

Pharmacodynamics

The principle of action of Velpanat is due to its chemical structure. In the early 2000s, technologies appeared that allowed us to study in detail the main components of the HCV pathogen and their role in the spread of the virus. The new antiviral drug Velpanat acts on two major non-structural proteins: NS5B and NS5A. This provides a quick virological response and a low risk of developing resistance. Sofosbuvir and velpatasvir (the first as an active metabolite) provide reliable inhibition of HCV replication. Patients'

effectiveness is

usually interested in how quickly using Velpanat kills the virus. According to clinical studies of the efficacy of sofosbuvir and velpatasvir, average efficiency receiving a stable virologic response (SVR) was 96-98% (depending on the condition of the liver). The maximum values were observed in patients with genotypes 2, 4-6, and the minimum - with type 3. With the genotype, a positive result was recorded in more than 95% of cases.

Resistance

The lack of effect (slow viral load, maintaining the same level or increasing VO) is associated with a mutation of the virus. The structure of the active components of the drug is similar to certain sections of the HCV RNA strand, therefore, a change in the position of amino acid residues reduces the therapeutic effect of the drug.

Where to buy Velpanat Generic Epclusa cost in India?

It is not recommended to purchase this medicine in the official pharmacies of the city. The drug is manufactured under license from the pharmaceutical giant Gilead Sciences and is sold at low Generic Epclusa Cost in many countries around the world. But the Indian company has put forward stringent conditions for drug manufacturers under license. Budget generics will not be delivered to a number of European states, including India..

Now genuine Velpanat can be bought by residents of India only in online pharmacies with delivery. The order is made out on the website or by calling the hotline.